Enhancing T-cell Culture to Accelerate Therapy Development
Reduce variability concerns with TheraPEAK® T-VIVO® Cell Culture Medium and achieve greater cell proliferation, viability, along with increased process efficiencies. Its novel formulation comprised of chemically-defined components and recombinant proteins is serum-free and non-animal origin (NAO), ensuring consistency and increased process control.
TheraPEAK® T-VIVO® Medium enhances the culture and expansion of:
- T cells
- CAR-T cells
- Peripheral blood lymphocytes (PBL)
- Tumor infiltrating lymphocytes (TIL)
With traceability documentation available, including Certificates of Analysis and a Drug Master File, TheraPEAK® T-VIVO® Cell Culture Medium simplifies processes, supports regulatory compliance, and scale up from preclinical development through to manufacturing.
Optimal performance across different platforms
T-cell expansion in TheraPEAK® T-VIVO® Medium compared with other commercial media in a gas-permeable cell expansion device
TheraPEAK® T-VIVO® Cell Culture Medium supports efficient T-cell expansion in a gas-permeable cell expansion device compared with various commercial media. All culture media are supplemented with recombinant human IL-2 (100 IU/mL). Each donor is represented by the ▲■● symbol. Human AB serum (5%) is also added to each medium for comparison purpose (black symbols). Medium G and RPMI-1640 do not support T cell growth without the supplementation of human AB serum.
Scale-up of T-cell expansion in rocking motion platform and spinner flask using TheraPEAK® T-VIVO® Medium
Full-scale T-cell expansion in spinner flask or rocking motion platform bioreactor. Peripheral blood mononuclear cells are activated via CD3 and CD28 and expanded with TheraPEAK® T-VIVO® Medium for up to 12 days. TheraPEAK® T-VIVO® Medium is supplemented with recombinant human IL-2 (100 IU/mL).
Instructions for Use
TheraPEAK® T-VIVO® Cell Culture Medium is supported with protocols, application data and our world-class scientific support team.
Contact us for a copy of the Instructions for Use to discover the medium’s versatility across different platforms and its easy-to-use formulation.
Sizes and packaging
TheraPEAK® T-VIVO® Cell Culture Medium is available in the following sizes:
Customisation of packaging for specific applications is available. Please contact us for additional information
Quality and safety
Quality and safety are crucial to allow reliable results in clinical processes and ultimately, protect patients’ lives. All TheraPEAK® Products are produced according to applicable GMP standards and follow the USP/EP guidance for cell and gene therapy raw materials. TheraPEAK® Media Products are produced at FDA registered manufacturing sites with an ISO 13485 certified quality management system..
Request information, a sample or a quote
Would you like to speak to one of our experts or receive a quote or sample to enhance your T cell culture? Please contact us and we will get back to you shortly.